Universitätsklinikum Knappschaftskrankenhaus Bochum

Publikationsliste

2023

• Lurati Buse GA, Mauermann E, Ionescu D, Szczeklik W, De Hert S, Filipovic M, Beck-Schimmer B, Spadaro S, Matute P, Bolliger D, Turhan SC, van Waes J, Lagarto F, Theodoraki K, Gupta A, Gillmann HJ, Guzzetti L, Kotfis K, Wulf H, Larmann J, Corneci D, Chammartin-Basnet F, Howell SJ; MET: Reevaluation for Perioperative Cardiac Risk investigators (u.a. Bergmann L, Unterberg M)
  Risk assessment for major adverse cardiovascular events after noncardiac surgery using self-reported functional capacity: international prospective cohort study
  Br J Anaesth. 2023 Apr 1:S0007-0912(23)00108-3.
  
• Anft M, Skrzypczyk S, Frahnert M, Fricke L, Zapka J, Kühn D, Koos B, Adamzik M, Pfaender S, Stervbo U, Westhoff TH, Babel N
  Significant Fade of Neutralizing Antibodies and Stable Cellular Immunity in 4 Times COVID-19 Vaccinated Noninfected Compared to COVID-19 Convalescent and 3 Times Vaccinated Hemodialysis Patients
  Kidney Int Rep. 2023 Mar;8(3):685-687.
  
• Le-Trilling VTK, Banchenko S, Paydar D, Leipe PM, Binting L, Lauer S, Graziadei A, Klingen R, Gotthold C, Bürger J, Bracht T, Sitek B, Jan Lebbink R, Malyshkina A, Mielke T, Rappsilber J, Spahn CM, Voigt S, Trilling M, Schwefel D
  Structural mechanism of CRL4-instructed STAT2 degradation via a novel cytomegaloviral DCAF receptor
  EMBO J. 2023 Mar 1;42(5):e112351.
  
• Aweimer A, Petschulat L, Jettkant B, Köditz R, Finkeldei J, Dietrich JW, Breuer T, Draese C, Frey UH, Rahmel T, Adamzik M, Buchwald D, Useini D, Brechmann T, Hosbach I, Bünger J, Ewers A, El-Battrawy I, Mügge A
  Mortality rates of severe COVID-19-related respiratory failure with and without extracorporeal membrane oxygenation in the Middle Ruhr Region of Germany
  Sci Rep. 2023 Mar 29;13(1):5143.
  
• von Groote T, Meersch M, Romagnoli S, Ostermann M, Ripollés-Melchor J, Schneider AG, Vandenberghe W, Monard C, De Rosa S, Cattin L, Rahmel T, Adamzik M, Parise D, Candela-Toha A, Haaker JG, Göbel U, Bernard A, Lumlertgul N, Fernández-Valdes-Bango P, Romero Bhathal I, Suarez-de-la-Rica A, Larmann J, Villa G, Spadaro S, Wulf H, Arndt C, Putensen C, García-Álvarez R, Brandenburger T, Siniscalchi A, Ellerkmann R, Espeter F, Porschen C, Sadjadi M, Saadat-Gilani K, Weiss R, Gerss J, Kellum J, Zarbock A; BigpAK-2 Investigators (u.a. Nowak H, Bergmann L, Unterberg M, Wolf A, Marko B)
  Biomarker-guided intervention to prevent acute kidney injury after major surgery (BigpAK-2 trial): study protocol for an international, prospective, randomised controlled multicentre trial
  BMJ Open. 2023 Mar 27;13(3):e070240.
  

2022

• Campos NS, Bluth T, Hemmes SNT, Librero J, Pozo N, Ferrando C, Ball L, Mazzinari G, Pelosi P, Gama de Abreu M, Schultz MJ, Serpa Neto A; REPEAT; investigators for the PROVHILO study; iPROVE study; PROBESE study investigators (u.a. Bergmann L, Moelders P, Robitzky L, Unterberg M); PROVE Network
  Intraoperative positive end-expiratory pressure and postoperative pulmonary complications: a patient-level meta-analysis of three randomised clinical trials
  Br J Anaesth. 2022 Jun;128(6):1040-1051.
  
• Schenz J, Rump K, Siegler BH, Hemmerling I, Rahmel T, Thon JN, Nowak H, Fischer D, Hafner A, Tichy L, Bomans K, Meggendorfer M, Koos B, von Groote T, Zarbock A, Fiedler MO, Zemva J, Larmann J, Merle U, Adamzik M, Mueller-Tidow C, Haferlach T, Leuschner F, Weigand MA
  Increased prevalence of clonal hematopoiesis of indeterminate potential in hospitalized patients with COVID-19
  Front Immunol. 2022;13:968778.
  
• Rump K, Spellenberg T, von Busch A, Wolf A, Ziehe D, Thon P, Rahmel T, Adamzik M, Koos B, Unterberg M
  AQP5-1364A/C Polymorphism Affects AQP5 Promoter Methylation
  Int J Mol Sci. 2022;23(19):11813.
  
• Thon P, Rump K, Knorr A, Dyck B, Ziehe D, Unterberg M, Nowak H, Bergmann L, Wolf A, Bazzi M, Orlowski J, Peters M, Zarbock A, Brenner T, Adamzik M, Rahmel T, Koos B
  The Distinctive Activation of Toll-Like Receptor 4 in Human Samples with Sepsis
  Cells. 2022;11(19):3020.
  
• Rump K, Adamzik M
  Epigenetic Mechanisms of Postoperative Cognitive Impairment Induced by Anesthesia and Neuroinflammation
  Cells 2022;11(19):2954.
  
• Bracht T, Kleefisch D, Schork K, Witzke KE, Chen W, Bayer M, Hovanec J, Johnen G, Meier S, Ko YD, Behrens T, Brüning T, Fassunke J, Buettner R, Uszkoreit J, Adamzik M, Eisenacher M, Sitek B
  Plasma Proteomics Enable Differentiation of Lung Adenocarcinoma from Chronic Obstructive Pulmonary Disease (COPD)
  Int J Mol Sci. 2022 Sep 24;23(19):11242.
  
• Nowak H, Wolf A, Rahmel T, Oprea G, Grause L, Moeller M, Gyarmati K, Mittler C, Zagler A, Lutz K, Loeser J, Saller T, Tryba M, Adamzik M, Hansen E, Zech N
  Therapeutic Suggestions During General Anesthesia Reduce Postoperative Nausea and Vomiting in High-Risk Patients - A Post hoc Analysis of a Randomized Controlled Trial
  Front Psychol. 2022 Jul 15;13:898326.
  
• Marko B, Heurich P, Thon P, Zimmer F, Bergmann L, Nowak H, Rump K, Koos B, Adamzik M, Unterberg M, Rahmel T
  The Pro-Inflammatory Deletion Allele of the NF-κB1 Polymorphism Is Characterized by a Depletion of Subunit p50 in Sepsis
  Int J Mol Sci. 2022 Jul 8;23(14):7559.
  
• Rump K, Holtkamp C, Bergmann L, Nowak H, Unterberg M, Orlowski J, Thon P, Bazzi Z, Bazzi M, Adamzik M, Koos B, Rahmel T
  Midazolam impacts acetyl-And butyrylcholinesterase genes: An epigenetic explanation for postoperative delirium?
  PLoS One. 2022 Jul 8;17(7):e0271119.
  
• Rahmel T, Kraft F, Haberl H, Achtzehn U, Brandenburger T, Neb H, Jarczak D, Dietrich M, Magunia H, Zimmer F, Basten J, Landgraf C, Koch T, Zacharowski K, Weigand MA, Rosenberger P, Ullrich R, Meybohm P, Nierhaus A, Kindgen-Milles D, Timmesfeld N, Adamzik M
  Intravenous IgM-enriched immunoglobulins in critical COVID-19: a multicentre propensity-weighted cohort study
  Crit Care. 2022 Jul 7;26(1):204.
  
• Bachler M, Asmis LM, Koscielny J, Lang T, Nowak H, Paulus P, Schewe JC, von Heymann C, Fries D
  Thromboprophylaxis with argatroban in critically ill patients with sepsis: a review
  Blood Coagul Fibrinolysis. 2022 Jul 1;33(5):239-256.
  
• Csizmarik A, Keresztes D, Nagy N, Bracht T, Sitek B, Witzke K, Puhr M, Tornyi I, Lázár J, Takács L, Kramer G, Sevcenco S, Maj-Hes A, Jurányi Z, Hadaschik B, Nyirády P, Szarvas T
  Proteome profiling of enzalutamide-resistant cell lines and serum analysis identified ALCAM as marker of resistance in castration-resistant prostate cancer
  Int J Cancer. 2022 Jun 11. Epub ahead of print.
  
• Meersch M, Weiss R, Küllmar M, Bergmann L, Thompson A, Griep L, Kusmierz D, Buchholz A, Wolf A, Nowak H, Rahmel T, Adamzik M, Haaker JG, Goettker C, Gruendel M, Hemping-Bovenkerk A, Goebel U, Braumann J, Wisudanto I, Wenk M, Flores-Bergmann D, Böhmer A, Cleophas S, Hohn A, Houben A, Ellerkmann RK, Larmann J, Sander J, Weigand MA, Eick N, Ziemann S, Bormann E, Gerß J, Sessler DI, Wempe C, Massoth C, Zarbock A 
  Effect of Intraoperative Handovers of Anesthesia Care on Mortality, Readmission, or Postoperative Complications Among Adults: The HandiCAP Randomized Clinical Trial
  JAMA. 2022 Jun 28;327(24):2403-2412.
  
• Varatnitskaya M, Fasel J, Müller A, Lupilov N, Shi Y, Fuchs K, Krewing M, Jung C, Jacob T, Sitek B, Bandow JE, Carroll KS, Hofmann E, Leichert LI
  An increase in surface hydrophobicity mediates chaperone activity in N-chlorinated
  RidA Redox Biol. 2022 Jul;53:102332.
  
• Schuhenn J, Meister TL, Todt D, Bracht T, Schork K, Billaud JN, Elsner C, Heinen N, Karakoese Z, Haid S, Kumar S, Brunotte L, Eisenacher M, Di Y, Lew J, Falzarano D, Chen J, Yuan Z, Pietschmann T, Wiegmann B, Uebner H, Taube C, Le-Trilling VTK, Trilling M, Krawczyk A, Ludwig S, Sitek B, Steinmann E, Dittmer U, Lavender KJ, Sutter K, Pfaender S
  Differential interferon-α subtype induced immune signatures are associated with suppression of SARS-CoV-2 infection
  Proc Natl Acad Sci U S A. 2022 Feb 22;119(8):e2111600119.
  
• Unterberg M, Rahmel T, Rump K, Wolf A, Haberl H, von Busch A, Bergmann L, Bracht T, Zarbock A, Ehrentraut SF, Putensen C, Wappler F, Köhler T, Ellger B, Babel N, Frey U, Eisenacher M, Kleefisch D, Marcus K, Sitek B, Adamzik M, Koos B, Nowak H; SepsisDataNet.NRW research group
  The impact of the COVID-19 pandemic on non-COVID induced sepsis survival
  BMC Anesthesiol. 2022;22(1):12.
  
• POSE-Study group (u.a. Bergmann L, Nowak H, Unterberg M, Rump K, Oprea G)
  Peri-interventional outcome study in the elderly in Europe: A 30-day prospective cohort study
  Eur J Anaesthesiol. 2022 Mar 1;39(3):198-209.​
  
• Kowark A, Berger M, Rossaint R, Schmid M, Coburn M; and the POSE-Study group (u.a. Bergmann L, Nowak H, Unterberg M, Rump K, Oprea G)
  Association between benzodiazepine premedication and 30-day mortality rate: A propensity-score weighted analysis of the Peri-interventional Outcome Study in the Elderly (POSE)
  Eur J Anaesthesiol. 2022 Mar 1;39(3):210-218.​
  
• Keresztes D, Csizmarik A, Nagy N, Módos O, Fazekas T, Bracht T, Sitek B, Witzke K, Puhr M, Sevcenco S, Kramer G, Shariat S, Küronya Z, Takács L, Tornyi I, Lázár J, Hadaschik B, Lászik A, Szűcs M, Nyirády P, Szarvas T
  Comparative proteome analysis identified CD44 as a possible serum marker for docetaxel resistance in castration-resistant prostate cancer
  J Cell Mol Med.2022 Feb;26(4):1332-1337.​
  

2021

• Funke L, Bracht T, Oeck S, Schork K, Stepath M, Dreesmann S, Eisenacher M, Sitek B, Schramm A
  NTRK1/TrkA Signaling in Neuroblastoma Cells Induces Nuclear Reorganization and Intra-Nuclear Aggregation of Lamin A/C
  Cancers 2021;13(21):5293.
  
• Unterberg M, Rahmel T, Kissinger T, Petermichl C, Bosmanns M, Niebius M, Schulze C, Jochum HP, Parohl N, Adamzik M, Nowak H
  Legionella contamination of a cold-water supplying system in a German university hospital – assessment of the superheat and flush method for disinfection
  J Prev Med Hyg. 2021;62:E751-E758.
  
• Magunia H, Lederer S, Verbuecheln R, Gilot BJ, Koeppen M, Haeberle HA, Mirakaj V, Hofmann P, Marx G, Bickenbach J, Nohe B, Lay M, Spies C, Edel A, Schiefenhövel F, Rahmel T, Putensen C, Sellmann T, Koch T, Brandenburger T, Kindgen-Milles D, Brenner T, Berger M, Zacharowski K, Adam E, Posch M, Moerer O, Scheer CS, Sedding D, Weigand MA, Fichtner F, Nau C, Prätsch F, Wiesmann T, Koch C, Schneider G, Lahmer T, Straub A, Meiser A, Weiss M, Jungwirth B, Wappler F, Meybohm P, Herrmann J, Malek N, Kohlbacher O, Biergans S, Rosenberger P
  Machine learning identifies ICU outcome predictors in a multicenter COVID-19 cohort
  Crit Care. 2021;25(1):295.
  
• Hirschberger S, Strauß G, Effinger D, Marstaller X, Ferstl A, Müller MB, Wu T, Hübner M, Rahmel T, Mascolo H, Exner N, Heß J, Kreth FW, Unger K, Kreth S
  Very-low-carbohydrate diet enhances human T-cell immunity through immunometabolic reprogramming
  EMBO Mol Med. 2021:e14323.
  
• Wernly B, Beil M, Bruno RR, Binnebössel S, Kelm M, Sigal S, van Heerden PV, Boumendil A, Artigas A, Cecconi M, Marsh B, Moreno R, Oeyen S, Bollen Pinto B, Szczeklik W, Leaver S, Walther SM, Schefold JC, Joannidis M, Fjølner J, Zafeiridis T, de Lange D, Guidet B, Flaatten H, Jung C; VIP2 study group (u.a. Rahmel T)
  Provision of critical care for the elderly in Europe: a retrospective comparison of national healthcare frameworks in intensive care units
  BMJ Open. 2021;11(6):e046909.
  
• Haas LEM, Boumendil A, Flaatten H, Guidet B, Ibarz M, Jung C, Moreno R, Morandi A, Andersen FH, Zafeiridis T, Walther S, Oeyen S, Leaver S, Watson X, Boulanger C, Szczeklik W, Schefold JC, Cecconi M, Marsh B, Joannidis M, Nalapko Y, Elhadi M, Fjølner J, Artigas A, de Lange DW; VIP2 study group (u.a. Rahmel T)
  Frailty is associated with long-term outcome in patients with sepsis who are over 80 years old: results from an observational study in 241 European ICUs
  Age Ageing. 2021:afab036.
  
• Lill JK, Thiebes S, Pohl JM, Bottek J, Subramaniam N, Christ R, Soun C, Gueler F, Zwanziger D, Hoffmann F, von Eggeling F, Bracht T, Sitek B, Hickey MJ, Hofnagel O, Engel DR
  Tissue-resident macrophages mediate neutrophil recruitment and kidney injury in shiga toxin-induced hemolytic uremic syndrome
  Kidney Int. 2021:S0085-2538(21)00453-1.
  
• Witzke KE, Großerueschkamp F, Gerwert K, Sitek B
  Application of Label-Free Proteomics for Quantitative Analysis of Urothelial Carcinoma and Cystitis Tissue
  Methods Mol Biol. 2021;2228:283-292.
  
• May C, Brosseron F, Chartowski P, Fuchs K, Meyer HE, Sitek B, Marcus K
  Differential Proteome Analysis Using 2D-DIGE
  Methods Mol Biol. 2021;2228:77-84.
  
• May C, Brosseron F, Pfeiffer K, Fuchs K, Meyer HE, Sitek B, Marcus K
  Proteome Analysis with Classical 2D-PAGE
  Methods Mol Biol. 2021;2228:53-62.
  
• Stepath M, Bracht T
  Application of SILAC Labeling in Phosphoproteomics Analysis.
  Methods Mol Biol. 2021;2228:167-183.
  
• Barkovits K, Chen W, Kohl M, Bracht T
  Targeted Protein Quantification Using Parallel Reaction Monitoring (PRM)
  Methods Mol Biol. 2021;2228:145-157
  
• Subramaniam N, Bottek J, Thiebes S, Zec K, Kudla M, Soun C, de Dios Panal E, Lill JK, Pfennig A, Herrmann R, Bruderek K, Rahmann S, Brandau S, Johansson P, Reinhardt HC, Dürig J, Seiffert M, Bracht T, Sitek B, Engel DR
  Proteomic and bioinformatic profiling of neutrophils in CLL reveals functional defects that predispose to bacterial infections
  Blood Adv. 2021;5(5):1259-1272.
  
• Massoth C, Saadat-Gilani K, Meersch M; HandiCAP Investigators (u.a. Lars Bergmann, Michael Adamzik, Astrid Thompson, Leonore Griep, Desiree Kusmierz, Hartmuth Nowak)
  Impact of handover of anesthesia care on adverse postoperative outcomes - The HandiCAP trial
  Anaesthesist. 2021;70(4):320-323. (Artikel in Deutsch)
  
• Funke L, Gnipp S, Ahrens M, Eisenacher M, Peters M, Sitek B, Bracht T
  Quantitative analysis of proteome dynamics in a mouse model of asthma
  Clin Exp Allergy. 2021 Nov;51(11):1471-1481.
  
• Wolf A, Selpien H, Haberl H, Unterberg M
  Does a combined intravenous-volatile anesthesia offer advantages compared to an intravenous or volatile anesthesia alone: a systematic review and meta-analysis
  BMC Anesthesiol. 2021;21(1):52.
  
• Korbmacher JG, Schulze-Raestrup U, Nowak H, Smektala R
  Osteosynthetic treatment of proximal femoral fractures: the timing of treatment is delayed in cases of pre-existing anticoagulation: Results of the data of external inpatient quality assurance from North Rhine-Westphalia with 24,786 cases within the framework of using secondary data
  Unfallchirurg. 2021 Aug;124(8):642-650. (Artikel in Deutsch)
  
• Nowak H, Vornweg S, Rump K, Rahmel T, Unterberg M, Koos B, Schenker P, Viebahn R, Adamzik M, Bergmann L
  The NFKB1 Promoter Polymorphism (-94ins/delATTG) Is Associated with Susceptibility to Cytomegalovirus Infection after Kidney Transplantation and Should Have Implications on CMV Prophylaxis Regimens
  Cells 2021;10(2):380.
  

2020

• Nowak H, Zech N, Asmussen S, Rahmel T, Tryba M, Oprea G, Grause L, Schork K, Moeller M, Loeser J, Gyarmati K, Mittler C, Saller T, Zagler A, Lutz K, Adamzik M, Hansen E
  Effect of therapeutic suggestions during general anaesthesia on postoperative pain and opioid use: multicentre randomised controlled trial
  BMJ 2020;371:m4284.
  
• Rahmel T, Marko B, Nowak H, Bergmann L, Thon P, Rump K, Kreimendahl S, Rassow J, Peters J, Singer M, Adamzik M, Koos B
  Mitochondrial dysfunction in sepsis is associated with diminished intramitochondrial TFAM despite its increased cellular expression
  Sci Rep. 2020;10(1):21029.
  
• Koos B, Moderegger EL, Rump K, Nowak H, Willemsen K, Holtkamp C, Thon P, Adamzik M, Rahmel T
  LPS-Induced Endotoxemia Evokes Epigenetic Alterations in Mitochondrial DNA That Impacts Inflammatory Response
  Cells. 2020;9(10):2282.
  
• Bruno RR, Wernly B, Beil M, Muessig JM, Rahmel T, Graf T, Meybohm P, Schaller SJ, Allgäuer S, Franz M, Westphal JG, Barth E, Ebelt H, Fuest K, Horacek M, Schuster M, Dubler S, Schering S, Wolff G, Steiner S, Rabe C, Dieck T, Lauten A, Sacher AL, Brenner T, Bloos F, Jánosi RA, Simon P, Utzolino S, Kelm M, De Lange DW, Guidet B, Flaatten H, Jung C
  Therapy limitation in octogenarians in German intensive care units is associated with a longer length of stay and increased 30 days mortality: A prospective multicenter study
  J Crit Care. 2020;60:58-63.
  
• Rahmel T, Hübner M, Koos B, Wolf A, Willemsen KM, Strauß G, Effinger D, Adamzik M, Kreth S
  Impact of carbohydrate-reduced nutrition in septic patients on ICU: study protocol for a prospective randomised controlled trial
  BMJ Open. 2020;10(7):e038532.
  
• Rump K, Rahmel T, Rustige AM, Unterberg M, Nowak H, Koos B, Schenker P, Viebahn R, Adamzik M, Bergmann L
  The Aquaporin3 Promoter Polymorphism -1431 A/G is Associated with Acute Graft Rejection and Cytomegalovirus Infection in Kidney Recipients Due to Altered Immune Cell Migration
  Cells. 2020;9(6):E1421.
  
• Apfelbacher C, Brandstetter S, Blecha S, Dodoo-Schittko F, Brandl M, Karagiannidis C, Quintel M, Kluge S, Putensen C, Bercker S, Ellger B, Kirschning T, Arndt C, Meybohm P, Weber-Carstens S; DACAPO study group (u.a. Adamzik M, Karlik J, Martini S, Robitzky L), Bein T
  uence of quality of intensive care on quality of life/return to work in survivors of the acute respiratory distress syndrome: prospective observational patient cohort study (DACAPO).
  BMC Public Health. 2020 Jun 5;20(1):861.
  
• Blecha S, Brandl M, Zeman F, Dodoo-Schittko F, Brandstetter S, Karagiannidis C, Bein T, Apfelbacher C; DACAPO Study Group (u.a. Adamzik M, Karlik J, Martini S, Robitzky L)
  Tracheostomy in patients with acute respiratory distress syndrome is not related to quality of life, symptoms of psychiatric disorders or return-to-work: the prospective DACAPO cohort study
  Ann Intensive Care. 2020 May 6;10(1):52.
  
• Selpien H, Unterberg M
  Perioperative Arzneimittelinteraktionen – was der Anästhesist wissen sollte
  Anasthesiol Intensivmed Notfallmed Schmerzther. 2020;55(5):289-299.
  
• Bergmann L, Nowak H, Siffert W, Peters J, Adamzik M, Koos B, Rahmel T
  Major Adverse Kidney Events Are Associated with the Aquaporin 5 -1364A/C Promoter Polymorphism in Sepsis: A Prospective Validation Study
  Cells. 2020;9(4):940.
  
• Iqbal K, Broeker A, Nowak H, Rahmel T, Nussbaumer-Proell A, Oesterreicher Z, Zeitlinger M, Wicha SG
  A pharmacometric approach to define target site-specific breakpoints for bacterial killing and resistance suppression integrating microdialysis, time-kill curves and heteroresistance data: A case study with moxifloxacin
  Clin Microbiol Infect 2020;S1198-743X(20)30093-8.
  
• Rahmel T, Schmitz S, Nowak H, Schepanek K, Bergmann L, Halberstadt P, Hörter S, Peters J, Adamzik M
  Long-term mortality and outcome in hospital survivors of septic shock, sepsis, and severe infections: The importance of aftercare
  PLoS One. 2020;15(2):e0228952.
  
• Guidet B, de Lange DW, Boumendil A, Leaver S, Watson X, Boulanger C, Szczeklik W, Artigas A, Morandi A, Andersen F, Zafeiridis T, Jung C, Moreno R, Walther S, Oeyen S, Schefold JC, Cecconi M, Marsh B, Joannidis M, Nalapko Y, Elhadi M, Fjølner J, Flaatten H; VIP2 study group (u.a. Rahmel T)
  The contribution of frailty, cognition, activity of daily life and comorbidities on outcome in acutely admitted patients over 80 years in European ICUs: the VIP2 study
  Intensive Care Med. 2020;46(1):57-69.
  

2019

• Rahmel T, Nowak H, Rump K, Koos B, Schenker P, Viebahn R, Adamzik M, Bergmann L
  The Aquaporin 5 -1364A/C Promoter Polymorphism Is Associated With Cytomegalovirus Infection Risk in Kidney Transplant Recipients
  Front Immunol. 2019;10:2871.
  
• Rump K, Unterberg M, Dahlke A, Nowak H, Koos B, Bergmann L, Siffert W, Schäfer ST, Peters J, Adamzik M, Rahmel T
  DNA methylation of a NF-κB binding site in the aquaporin 5 promoter impacts on mortality in sepsis
  Sci Rep. 2019;9(1):18511.
  
• Nowak H, Weidemann C, Martini S, Oesterreicher ZA, Dorn C, Adamzik M, Kees F, Zeitlinger M, Rahmel T
  Repeated determination of moxifloxacin concentrations in interstitial space fluid of muscle and subcutis in septic patients
  J Antimicrob Chemother. 2019;74(9):2681-2689.
  
• Brandstetter S, Dodoo-Schittko F, Brandl M, Blecha S, Bein T, Apfelbacher C; DACAPO study group (u.a. Adamzik M, Karlik J, Martini S, Robitzky L)
  Ambulatory and stationary healthcare use in survivors of ARDS during the first year after discharge from ICU: findings from the DACAPO cohort
  Ann Intensive Care. 2019;9(1):70
  
• Unterberg M, Nowak H
  Increased Arterial Blood-Pressure Previous to Elective Surgery - How to Proceed?
  Anasthesiol Intensivmed Notfallmed Schmerzther. 2019;54(5):348-354 (Artikel in Deutsch)
  
• Writing Committee for the PROBESE Collaborative Group of the PROtective VEntilation Network (PROVEnet) for the Clinical Trial Network of the European Society of Anaesthesiology, Bluth T, Serpa Neto A, Schultz MJ, Pelosi P, Gama de Abreu M; Investigators (u.a. Bergmann L, Ebner F, Mölders P, Robitzky L, Unterberg M)
  Effect of Intraoperative High Positive End-Expiratory Pressure (PEEP) With Recruitment Maneuvers vs Low PEEP on Postoperative Pulmonary Complications in Obese Patients: A Randomized Clinical Trial
  JAMA. 2019;322(18):1829-1830.
  
• Wolf A, Mölders P, Yilmaz U
  Stroke Thrombectomy: Anaesthesiologic Aspects
  Anasthesiol Intensivmed Notfallmed Schmerzther. 2019 Apr;54(4):283-293 (Artikel in Deutsch)
  
• Holtkamp C, Koos B, Unterberg M, Rahmel T, Bergmann L, Bazzi Z, Bazzi M, Bukhari H, Adamzik M, Rump K
  A novel understanding of postoperative complications: In vitro study of the impact of propofol on epigenetic modifications in cholinergic genes
  PLoS One. 2019;14(5):e0217269
  
• Rahmel T, Koniusch A, Schwertner M, Oprea G, Adamzik M, Nowak H
  Evaluation of inhaled salbutamol effectiveness under supportive use of electrical impedance tomography in ventilated ICU patients: study protocol for a randomised controlled clinical trial
  BMJ Open. 2019;9(3):e026038
  
• Rahmel T, Rump K, Peters J, Adamzik M
  Aquaporin 5 -1364A/C Promoter Polymorphism Is Associated with Pulmonary Inflammation and Survival in Acute Respiratory Distress Syndrome
  Anesthesiology. 2019;130(3):404-413
  
• Kalvelage C, Zacharowski K, Bauhofer A, Gockel U, Adamzik M, Nierhaus A, Kujath P, Eckmann C, Pletz MW, Bracht H, Simon TP, Winkler M, Kindgen-Milles D, Albertsmeier M, Weigand M, Ellger B, Ragaller M, Ullrich R, Marx G
  Personalized medicine with IgGAM compared with standard of care for treatment of peritonitis after infectious source control (the PEPPER trial): study protocol for a randomized controlled trial
  Trials. 2019;20(1):156
  

2018

• Fichtner F, Moerer O, Laudi S, Weber-Carstens S, Nothacker M, Kaisers U; Investigators and the Guideline Group on Mechanical Ventilation and Extracorporeal Membrane Oxygenation in Acute Respiratory Insufficiency (u.a. Adamzik M)
  Mechanical Ventilation and Extracorporeal Membrane Oxygena tion in Acute Respiratory Insufficiency
  Dtsch Arztebl Int. 2018;115(50):840-847
  
• Rahmel T, Nowak H, Rump K, Siffert W, Peters J, Adamzik M
  The aquaporin 5 -1364A/C promoter polymorphism impacts on resolution of acute kidney injury in pneumonia evoked ARDS
  PLoS One. 2018;13(12):e0208582
  
• Donauer K, Bomberg H, Wagenpfeil S, Volk T, Meissner W, Wolf A
  Regional vs. General Anesthesia for Total Knee and Hip Replacement: An Analysis of Postoperative Pain Perception from the International PAIN OUT Registry
  Pain Pract. 2018;18(8):1036-1047
  
• Mölders P, Alders BJ
  Synopsis Neuroanesthesia: Brain, Anesthetics and Skills
  Anasthesiol Intensivmed Notfallmed Schmerzther. 2018;53(9):618-630 (Artikel in Deutsch)
  
• Muessig JM, Nia AM, Masyuk M, Lauten A, Sacher AL, Brenner T, Franz M, Bloos F, Ebelt H, Schaller SJ, Fuest K, Rabe C, Dieck T, Steiner S, Graf T, Jánosi RA, Meybohm P, Simon P, Utzolino S, Rahmel T, Barth E, Schuster M, Kelm M, Jung C
  Clinical Frailty Scale (CFS) reliably stratifies octogenarians in German ICUs: a multicentre prospective cohort study
  BMC Geriatr. 2018;18(1):162
  
• Nowak H, Unterberg M
  Oral Anticoagulants: Management of Elective and Emergency Surgery
  Anasthesiol Intensivmed Notfallmed Schmerzther. 2018;53(7):543-550 (Artikel in Deutsch)
  
• Schulte K, Borzikowsky C, Rahmel A, Kolibay F, Polze N, Fränkel P, Mikle S, Alders B, Kunzendorf U, Feldkamp T
  Decline in organ donation in Germany - a nationwide secondary analysis of all inpatient cases
  Dtsch Arztebl Int 2018;115:463-468
  
• Rahmel T, Rump K, Adamzik M, Peters J, Frey UH
  Increased circulating microRNA-122 is associated with mortality and acute liver injury in the acute respiratory distress syndrome
  BMC Anesthesiol. 2018;18(1):75
  
• Bergmann L
  Safe Vascular Access - the Guideline of the Association of Anaesthesists of Great Britain and Ireland 2016
  Anasthesiol Intensivmed Notfallmed Schmerzther. 2018;53(6):458-465 (Artikel in Deutsch)
  
• Klenke S, Eul S, Peters J, Neumann T, Adamzik M, Frey UH
  Circulating miR-192 is a prognostic marker in patients with ischemic cardiomyopathy
  Future Cardiol. 2018;14(4):283-289
  
• Rahmel T, Schäfer ST, Frey UH, Adamzik M, Peters J
  Increased circulating microRNA-122 is a biomarker for discrimination and risk stratification in patients defined by sepsis-3 criteria
  PLoS One 2018;13(5):e0197637
  
• Guidet B, Flaatten H, Boumendil A, Morandi A, Andersen FH, Artigas A, Bertolini G, Cecconi M, Christensen S, Faraldi L, Fjølner J, Jung C, Marsh B, Moreno R, Oeyen S, Öhman CA, Pinto BB, Soliman IW, Szczeklik W, Valentin A, Watson X, Zafeiridis T, De Lange DW; VIP1 study group (u.a. Rahmel T)
  Withholding or withdrawing of life-sustaining therapy in older adults (≥ 80 years) admitted to the intensive care unit
  Intensive Care Med. 2018;44(7):1027-1038
  
• Dodoo-Schittko F, Brandstetter S, Brandl M, Blecha S, Quintel M, Weber-Carstens S, Kluge S, Kirschning T, Muders T, Bercker S, Ellger B, Arndt C, Meybohm P, Adamzik M, Goldmann A, Karagiannidis C, Bein T, Apfelbacher C; DACAPO Study Group (u.a. Karlik J, Martini S, Robitzky L)
  German-wide prospective DACAPO cohort of survivors of the acute
  respiratory distress syndrome (ARDS): a cohort profile
  BMJ Open 2018;8(4):e019342
  
• Rump K, Adamzik M
  Function of aquaporins in sepsis: a systematic review
  Cell Biosci 2018;8:10
  
• Blecha S, Dodoo-Schittko F, Brandstetter S, Brandl M, Dittmar M, Graf BM, Karagiannidis C, Apfelbacher C, Bein T; DACAPO Study Group (u.a. Adamzik M, Karlik J, Martini S, Robitzky L)
  Quality of inter-hospital transportation in 431 transport survivor patients suffering from acute respiratory distress syndrome referred to specialist centers
  Ann Intensive Care 2018;8(1):5
  
• Rahmel T
  SSC International Guideline 2016 - Management of Sepsis and Septic Shock
  Anasthesiol Intensivmed Notfallmed Schmerzther. 2018;53(2):142-148 (Artikel in Deutsch)